BPC-157

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BPC-157 is a synthetic pentadecapeptide derived from a sequence found in human gastric juice. It is widely referenced in preclinical research for its stability and interactions with cellular signaling pathways related to tissue integrity, angiogenesis, and gastrointestinal models. For laboratory research use only.

For research purposes only. Not for human consumption

Research Overview

BPC-157, also known as Body Protection Compound-157, has been extensively studied in in vitro and animal research models for its role in cellular protection and repair mechanisms. Published studies suggest that BPC-157 interacts with nitric oxide (NO) signaling pathways and modulates angiogenic responses, making it relevant in vascular, connective tissue, and wound-healing research contexts [1][2]. Additional investigations have explored its effects on fibroblast migration, endothelial cell activity, and cytoprotective responses under stress conditions. Due to its high stability in gastric environments, BPC-157 is frequently referenced in gastrointestinal and mucosal integrity research models [3].

Applications in Scientific Research

In preclinical literature, BPC-157 has been evaluated across multiple experimental domains, including gastrointestinal injury models, musculoskeletal tissue studies, and neurovascular research frameworks. Animal studies have examined its influence on tendon-to-bone healing, muscle regeneration, and microvascular perfusion following injury [4][5]. Other research has explored its interaction with growth factor signaling, oxidative stress markers, and inflammatory mediators under controlled laboratory conditions [6]. These findings have positioned BPC-157 as a peptide of interest for researchers studying tissue response, cellular resilience, and adaptive repair mechanisms. This compound is supplied strictly for research and analytical purposes and is not intended for human or veterinary use.

Referenced Citations

  1. Sikiric P. et al. “Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract.” Journal of Physiology-Paris.
    https://pubmed.ncbi.nlm.nih.gov/10866030/
  2. Sikiric P. et al. “The effect of pentadecapeptide BPC 157 on the nitric oxide system.” Journal of Physiology-Paris.
    https://pubmed.ncbi.nlm.nih.gov/15288738/
  3. Seiwerth S. et al. “Cytoprotection and adaptive responses in gastric mucosa mediated by BPC 157.” Digestive Diseases and Sciences.
    https://pubmed.ncbi.nlm.nih.gov/9863572/
  4. Chang C.H. et al. “BPC-157 enhances tendon fibroblast outgrowth and cell survival.” Journal of Orthopaedic Research.
    https://pubmed.ncbi.nlm.nih.gov/23381918/
  5. Staresinic M. et al. “Accelerated healing of transected rat Achilles tendon by BPC-157.” Journal of Orthopaedic Research.
    https://pubmed.ncbi.nlm.nih.gov/17975857/
  6. Vukojevic J. et al. “BPC-157 modulates inflammatory and oxidative stress responses.” Biomedicine & Pharmacotherapy.
    https://pubmed.ncbi.nlm.nih.gov/30340920/
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