$89.00
IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 engineered with an Arg³ substitution and extended N-terminal sequence to increase stability. It is widely referenced in cellular and molecular research focused on growth factor signaling, cell proliferation, and receptor–ligand interactions. Supplied strictly for laboratory research use only.
For research purposes only. Not for human consumption
IGF-1 LR3 differs from native IGF-1 by the substitution of arginine at position three and the addition of a 13-amino-acid extension, modifications shown to reduce binding to IGF-binding proteins and extend functional activity in experimental systems [1]. In preclinical and in vitro studies, IGF-1 LR3 is used to investigate insulin-like growth factor-1 receptor (IGF-1R) activation, PI3K/Akt and MAPK signaling cascades, and cellular growth responses [2]. These properties make IGF-1 LR3 a common reference compound in studies examining growth factor potency and receptor signaling dynamics.
In laboratory research models, IGF-1 LR3 is primarily utilized in cell culture studies, muscle and connective tissue research, and regenerative biology frameworks. Published literature explores its role in myoblast differentiation, protein synthesis signaling, and cell survival pathways under controlled experimental conditions [3]. Additional studies examine IGF-1 analogs in neurobiology, bone metabolism, and developmental biology research, focusing on receptor specificity and downstream transcriptional responses [4][5]. These investigations position IGF-1 LR3 as a valuable tool for researchers studying insulin-like growth factor biology and growth factor analog design. This compound is not intended for human or veterinary use.
